To estimate a safe minimum hospital volume for hospitals performing coronary artery bypass graft () surgery.
Hospital data on all publicly funded in five European countries, 2007–2009 (106,149 patients).
Hierarchical logistic regression models to estimate the relationship between hospital volume and mortality, allowing for case mix. Segmented regression analysis to estimate a threshold.
The 30‐day in‐hospital mortality rate was 3.0 percent overall, 5.2 percent (95 percent : 4.0–6.4) in low‐volume hospitals, and 2.1 percent (95 percent : 1.8–2.3) in high‐volume hospitals. There is a significant curvilinear relationship between volume and mortality, flatter above 415 cases per hospital per year.
There is a clear relationship between hospital volume and mortality in Europe, implying a “safe” threshold volume of 415 cases per year.